Effects of anesthetic choice on inflammatory response in cardiac surgery

نویسندگان

  • Elif Doğan Baki
  • Remziye Gül Sivaci
  • Serdar Kokulu
  • Yüksel Ela
  • Mustafa Aldemir
  • Elif Dogan Baki
چکیده

Cardiac surgery is associated with the development of a systemic inflammatory response. The cytokine response in cardiac surgery patients is well explained and is dominated by the pro-inflammatory cytokines tumour necrosis factor (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8), and the antiinflammatory cytokine interleukin-10 (IL-10). The release of these cytokines has been related to the development of complications after cardiopulmonary bypass (CPB). In addition to many factors, choice of anesthetic agents affects immune response in cardiac surgery. This article summarizes recently published literature concerning inflammatory cytokines associated with cardiopulmonary bypass, use of anesthetic management techniques and their effects on inflammatory response in cardiac surgery.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Studies on thiopentone and midazolam hemodynamic response during induction of anesthesia in patients with coronary artery disease

Background: Induction of anesthesia in patients that undergo cardiac surgery has more risk than others, because of specific cardiovascular effects of the anesthetic drugs and the preoperative state of these patients, so the hemodynamic stability is very important in these patients. It seems that midazolam have less cardiovascular side effects than thiopentone. In this study, the effects of mid...

متن کامل

Systemic Inflammatory Response Syndrome Due to Surgery and its Effective Therapeutic Approaches

Introduction: Various lesions trigger an inflammatory response in the host body. These injuries include surgical stress Surgery exerts stress on the body. Systemic inflammatory syndrome is a reflection of the degree of surgical stress and as a system of assessing the severity of postoperative stress. Regular complexes of inflammatory polypeptide molecules contribute to the development of this i...

متن کامل

Investigating the Knowledge and Performance of Personnel and Students Anesthetic About the Complications of Oral Ginger in Surgery and Anesthesi

Background: Ginger from the Zingiberaceae family is abundantly found in the diet of the people of the world and has known properties such as: immune system, anti-cancer, anti-inflammatory, blood sugar and lipid raiser, anti-inflammatory and antioxidant properties. Despite these properties, new research has shown the effects of increased bleeding, anticoagulation. all of which can be attributed ...

متن کامل

Fares KM , Hasan - Ali H , Bakry R ( 2013 ) The Effect of Anesthetic Technique on Cardiac Troponin - T and Systemic Inflammatory Response after Major Abdominal Cancer Surgery

Objectives: this study aims at assessment of acute inflammatory response; measured by high sensitivity C-reactive protein (hs-CRP), and myocardial injury; measured by serum cardiac troponin-T (Tn-T) in patients undergoing elective major abdominal cancer surgery with general anaesthesia or combined general and lumbar epidural anesthesia. Methods: The study included 60 ischemic patients undergoin...

متن کامل

ثبات همودینامیک با کدام رژیم هوشبری در جراحی پیوند رگ‌های کرونر قلب بیماران تحت درمان با بتا-بلوکر بیشتراست؟سوفنتانیل سیس - آتراکوریوم یا سوفنتانیل-پانکرونیوم

    Background and Aim: Hemodynamic stability during anesthesia and operation is the most important aim of anesthesiologists. Every anesthetic drug has its own hemodynamic effects. The interaction of these drugs with each other and with preoperative drugs of the patients, may cause critical changes in patient's hemodynamic status. For a perfect anesthesia induction, while using high doses of op...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015